Implementation trials disparity in Africa
- Daniel Obua+−
- Joyce Nakitende
- Patrick Vuzara
- Timothy Adeyemi
- Victoria Nakalanzi+−
- Temitope Ogunnupebi
- Joy Happy Banonya
- Winnifred Akello
- Fiona Agweng
- Jonah Ainembabazi
- Mahad Muweesi
- Malinga Odong
- Joyce Nayiga
- Solomon Wani
- Mercy Tebamifor
- Ishmael Gumbo
- Julius Opolot
- Abiola Fafolahan
- Martha Nakyagaba Mutumba
- Redie Kidane
- Eleanor Sabuka
- Sandra Mwebe
- Felix Kofi Awuriki
- John Francis Kimuli
- Frank Matovu
- Getaneh Simachew
- Mary Nafuna
- Joy Osifo
- Angeth Achiek Kut
- Pius Kungu
- Boaz Mwesigwa
- James Arinaitwe
- Annette Kyomuhangi
- Julius Muhwezi
- Chipo Nkwemu
- Lauryn Nsenga
- Eyasu Menamo
- Daisy Wannyana
- Ronald Nuwamanya
Versions
- 2026-05-16 (3)
- 2026-05-16 (2)
- 2026-04-12 (1)
Keywords
trials
Implentation
disparity
Africa
How to Cite
Abstract
The know-do gap refers to a situation where there is failure to apply knowledge to improve people’s health (Kebede et al., 2014). There is a need to close the Know-do gap in Africa. We conducted a cross-sectional audit and analysis of all conducted trials registered on clinictrials.gov through April 2026. African countries conducted only 72 implementation trials compared 2338 in the United States of America, a 32-fold absolute trial volume gap. More implementation research is needed to close the large existing know-do gap in Africa.
References
Kebede, D., Zielinski, C., Mbondji, P. E., Piexoto, M., Kouvividila, W., & Lusamba-Dikassa, P.-S. (2014). The way forward – narrowing the knowledge gap in sub-Saharan Africa to strengthen health systems. Journal of the Royal Society of Medicine, 107(1_suppl), 10–12. https://doi.org/10.1177/0141076813512818
Sáenz V., Patino, C. M., & Carvalho Ferreira J. (2021). Implementation research and its role in public health and health policies. Jornal Brasileiro de Pneumologia, e20210443. https://doi.org/10.36416/1806-3756/e20210443

This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2026 Daniel Obua, Joyce Nakitende, Patrick Vuzara , Timothy Adeyemi, Victoria Nakalanzi, Temitope Ogunnupebi , Joy Happy Banonya , Winnifred Akello , Fiona Agweng , Jonah Ainembabazi , Mahad Muweesi , Malinga Odong , Joyce Nayiga , Solomon Wani , Mercy Tebamifor , Ishmael Gumbo, Julius Opolot, Abiola Fafolahan , Martha Nakyagaba Mutumba , Richard Ssempala , Redie Kidane , Pius Kungu, Sandra Mwebe, Boru Wato , Felix Kofi Awuriki , John Francis Kimuli, Frank Matovu, Getaneh Simachew , Mary Nafuna , Joy Osifo , Angeth Achiek Kut , Boaz Mwesigwa , Eleanor Sabuka , James Arinaitwe , Annette Kyomuhangi, Julius Muhwezi , Chipo Nkwemu , Lauryn Nsenga, Eyasu Menamo , Daisy Wannyana , Ronald Nuwamanya
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